Frey J, Einsfelder B
Eur J Biochem. 1984 Jan 2;138(1):213-6. doi: 10.1111/j.1432-1033.1984.tb07903.x.
Binding studies on diploid human fibroblasts with human immunoglobulin G (IgG) demonstrate the existence of a specific receptor for this class of immunoglobulin. The receptor preferentially binds aggregated human IgG and recognizes these complexes via the Fc portion of the molecule. Cytomegalovirus infection of diploid human fibroblasts results in a more than 100-fold increase in the number of IgG-receptors present on the cell surface. The binding of aggregated IgG by these newly expressed receptors exhibits the characteristics of the binding mediated by the receptors detectable in uninfected cells.
对二倍体人成纤维细胞与人免疫球蛋白G（IgG）的结合研究表明，存在这类免疫球蛋白的特异性受体。该受体优先结合聚集的人IgG，并通过分子的Fc部分识别这些复合物。人二倍体成纤维细胞的巨细胞病毒感染导致细胞表面存在的IgG受体数量增加100倍以上。这些新表达的受体对聚集IgG的结合表现出未感染细胞中可检测到的受体介导的结合特征。
