Saito R, Davis B K, Ollapally E P
Hum Pathol. 1984 Jan;15(1):87-9. doi: 10.1016/s0046-8177(84)80336-6.
An unusual adenosquamous carcinoma originating in the prostate of a 70-year-old man is described. Four years prior to the development of this lesion, a diagnosis of adenocarcinoma had been established by needle biopsy and the patient had been treated with radiation. Light microscopic examination revealed a pattern of adenocarcinoma predominant in the periurethral region and squamous cell carcinoma at the periphery. The latter neoplastic component involved the bladder and rectum and extended to the pelvic wall. Immunoperoxidase staining for prostatic acid phosphatase occurred in both cellular components, and electron microscopic examination confirmed the squamous differentiation of tumor cells.
本文描述了一例起源于一名70岁男性前列腺的罕见腺鳞癌。在该病变出现的四年前，经针吸活检确诊为腺癌，患者接受了放射治疗。光镜检查显示，腺癌模式在尿道周围区域占主导，而外周为鳞状细胞癌。后一种肿瘤成分累及膀胱和直肠，并延伸至盆腔壁。两种细胞成分均出现前列腺酸性磷酸酶免疫过氧化物酶染色，电镜检查证实肿瘤细胞存在鳞状分化。
