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类固醇与特发性面神经麻痹

Steroids and idiopathic facial paralysis.

作者信息

Stankiewicz J A

出版信息

Otolaryngol Head Neck Surg. 1983 Dec;91(6):672-7. doi: 10.1177/019459988309100615.

DOI:10.1177/019459988309100615
PMID:6320082
Abstract

The face proclaims to the world an individual's identity and as such is the most conspicuous part of his anatomy. No wonder, then, that idiopathic facial paralysis is a frightening experience for the patient. Ever since it was first noted, all manners of measures have been used to bring about early and full recovery. Unfortunately, none of these treatments is effective. Following Rothendler's case description in 1951, a multitude of papers have appeared, evaluating the effectiveness of steroids in idiopathic facial paralysis. This article evaluates 92 of these papers. Only a few properly controlled, randomized prospective studies were available. Their main conclusion was that steroid treatment was not more beneficial than conventional treatment. But several less valid prospective and retrospective studies have suggested that steroid treatment is beneficial. The definitive, statistically valid study of the benefits of steroids in treating has yet to be performed. Until then steroid treatment of this condition will continue to be controversial.

摘要

面部向世界宣告着一个人的身份,因此它是人体最显眼的部位。难怪特发性面神经麻痹对患者来说是一种可怕的经历。自从它首次被发现以来,人们采取了各种各样的措施来实现早期和完全康复。不幸的是,这些治疗方法都没有效果。自1951年罗滕德勒描述该病例以来,出现了大量论文,评估类固醇在特发性面神经麻痹中的疗效。本文对其中92篇论文进行了评估。仅有少数经过适当对照的随机前瞻性研究。它们的主要结论是,类固醇治疗并不比传统治疗更有益。但一些有效性稍逊的前瞻性和回顾性研究表明,类固醇治疗是有益的。关于类固醇治疗益处的权威性、具有统计学意义的研究尚未进行。在此之前,这种疾病的类固醇治疗仍将存在争议。

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1
Steroids and idiopathic facial paralysis.类固醇与特发性面神经麻痹
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