Caster W O, Hoff L A, Wade A E
Int J Vitam Nutr Res. 1978;48(1):54-61.
Rats were fed diets resembling a normal human diet, except that, in a complete factorial fashion, safflower oil and/or mineral oil were substituted for part of the fat, while fructose, lactose and/or cellulose were substituted for carbohydrate, and zein was substituted for milk protein. Food intake and weight gain were not influenced by cellulose and mineral oil, but zein decreased both substantially. Plasma cholesterol was unchanged by safflower oil or mineral oil but was decreased by fructose. Plasma glucose was reduced as the starch-to-sugar ratio increased. The rate of aniline metabolism was increased by lactose and/or zein, but the rate of ethylmorphine metabolism was decreased by safflower oil or mineral oil.
给大鼠喂食类似正常人类饮食的食物，但以完全析因的方式，用红花油和/或矿物油替代部分脂肪，用果糖、乳糖和/或纤维素替代碳水化合物，并用玉米醇溶蛋白替代乳蛋白。纤维素和矿物油不影响食物摄入量和体重增加，但玉米醇溶蛋白会显著降低二者。红花油或矿物油不会改变血浆胆固醇水平，但果糖会降低血浆胆固醇水平。随着淀粉与糖的比例增加，血浆葡萄糖水平降低。乳糖和/或玉米醇溶蛋白会提高苯胺代谢率，但红花油或矿物油会降低乙基吗啡代谢率。
