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[妊娠男性化黄体瘤。与多囊卵巢的关系]

[Virilizing luteoma of pregnancy. Relation to polycystic ovaries].

作者信息

Guilmot J L, Avignon J P, Lecomte P, Boscq G, Billard J J, Delsol M

出版信息

Sem Hop. 1983 Dec 1;59(44):3053-7.

PMID:6320393
Abstract

Luteoma of pregnancy is a benign uncommon ovarian tumor which develops during pregnancy and disappears completely after delivery. It can virilize the mother and female foetus. The coexistence of this ovarian tumor with polycystic ovarian disease is well known but no causal relation has been demonstrated. In polycystic ovarian disease, luteinization is the result of persistent stimulation of the ovary by elevated levels of LH, whereas HCG has been suggested as a factor in the pathogenesis of luteoma. Though not a requisite factor, ovarian polycystic disease promotes the development of luteoma. However, the role of other hormonal and biochemical factors is still unknown.

摘要

妊娠黄体瘤是一种良性的罕见卵巢肿瘤,在孕期发生,产后完全消失。它可使母亲和女性胎儿男性化。这种卵巢肿瘤与多囊卵巢疾病并存是众所周知的,但尚未证实有因果关系。在多囊卵巢疾病中,黄素化是由于促黄体生成素水平升高对卵巢持续刺激的结果,而人绒毛膜促性腺激素被认为是黄体瘤发病机制中的一个因素。虽然不是必要因素,但卵巢多囊疾病会促进黄体瘤的发展。然而,其他激素和生化因素的作用仍不清楚。

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