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[蜗牛神经元体膜快速钾通道门控机制的热力学特性]

[Thermodynamic characteristics of the gating mechanisms of fast potassium channels of somatic membranes of snail neurons].

作者信息

Magura I S, Prevarskaia N B, Dub V A

出版信息

Neirofiziologiia. 1983;15(6):563-70.

PMID:6322018
Abstract

The fast potassium current conductance was treated as a system obeying n3 kinetics. The steady-state arrangement of the gating charges have been analyzed in terms of a Boltzmann distribution with two allowed configurations. Rate equations were obtained using the transition rate theory and assuming that each reaction was rate limited by only one energy barrier. These equations gave a simple exponential function for the voltage dependence of the rates. The single-barrier equations were used to estimate the energies of formation of the transition state.

摘要

快速钾电流电导被视为一个遵循n3动力学的系统。门控电荷的稳态排列已根据具有两种允许构型的玻尔兹曼分布进行了分析。使用跃迁速率理论并假设每个反应仅受一个能垒的速率限制来获得速率方程。这些方程给出了速率电压依赖性的简单指数函数。单能垒方程用于估计过渡态形成的能量。

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1
[Thermodynamic characteristics of the gating mechanisms of fast potassium channels of somatic membranes of snail neurons].[蜗牛神经元体膜快速钾通道门控机制的热力学特性]
Neirofiziologiia. 1983;15(6):563-70.
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J Membr Biol. 2002 Nov 1;190(1):17-28. doi: 10.1007/s00232-002-1021-9.
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[Surface charge in the region where the calcium channels of mollusk neuron somatic membrane are located].[软体动物神经元体细胞膜钙通道所在区域的表面电荷]
Dokl Akad Nauk SSSR. 1980;250(2):464-7.
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