Chomette G, Auriol M, Tereau Y, Bertrand J C, Guilbert F
Rev Stomatol Chir Maxillofac. 1983;84(6):336-40.
One case of myoepithelioma of the submandibular gland is reported. The tumor was composed of mixed spindle-shaped and plasmacytoid cells. The electron microscopy showed intracytoplasmic myofilaments, with variations in number and in repartition from one cell to another. Histoenzymologically, ATPasic and alkaline phosphatase activities could not be demonstrated in these poor differentiated myoid cells. Usually, the tumor has a good behavior. It represents a rare tumor (7 cases - 0,8% - in a retrospective study of 850 salivary gland tumors). Without demonstration of myofilaments by ultrastructural analysis, the diagnosis of such a tumor is very difficult. Taking into consideration new concepts about the myoepithelial cell, the histogenesis of this neoplasm is discussed.
本文报告1例下颌下腺肌上皮瘤。肿瘤由梭形细胞和浆细胞样细胞混合组成。电镜检查显示胞质内有肌丝,其数量和分布在不同细胞间存在差异。组织酶学检查显示,这些低分化肌样细胞中未检测到ATP酶和碱性磷酸酶活性。通常,该肿瘤生物学行为良好。它是一种罕见肿瘤(在一项对850例涎腺肿瘤的回顾性研究中占7例,占0.8%)。若未通过超微结构分析证实肌丝的存在,此类肿瘤的诊断将非常困难。结合关于肌上皮细胞的新概念,对该肿瘤的组织发生进行了讨论。