[Metabolic reaction of leukocytes in the course of experimental traumatic shock of varying intensity and on exposure to obzidan].

In stress-resistant animals exposed to 5-minute immobilization, the metabolic reaction of leukocytes was marked by an increase in the activity of G-6-PDH, hexokinase (HK), cytochrome oxidase (CCO) accompanied by a decrease in the activity of succinate dehydrogenase (SDH). In stress-labile animals, there was a decrease in the activity of G-6-PDH, HK, CCO with an increase in the activity of SDH. The orientation of enzymatic processes in leukocytes of stress-labile animals after immobilization and of stress-resistant animals following intravenous injection of propranolol was discovered to be similar. After propranolol injection leukocytes did not show any glucose, while the activity of G-6-PDH, HK and CCO descended. Injection of propranolol decreased the animal's resistance to traumatic shock. In stress-resistant animals exposed to trauma after the blockade of beta-adrenoreactive structures, the metabolic reaction was marked by low mobility restitution of energy processes as was the case in stress-labile animals during the development of a severe shock.