猿猴轮状病毒SA11的基因组异质性
Genomic heterogeneity of simian rotavirus SA11.
作者信息
Pereira H G, Azeredo R S, Fialho A M, Vidal M N
出版信息
J Gen Virol. 1984 Apr;65 ( Pt 4):815-8. doi: 10.1099/0022-1317-65-4-815.
PMID:6323623
Abstract
A preparation of simian rotavirus SA11 was shown to contain, in addition to the normal 11 genome segments, an RNA species with electrophoretic mobility slightly higher than that of segment 4. Limiting dilution passages allowed the separation of two virus clones distinguishable from each other by the electrophoretic mobility of that genome segment. Possible implications of this finding in virus behaviour and in the comparison of rotaviruses by RNA electrophoresis are discussed.
摘要
已证明，猿猴轮状病毒SA11制剂除了含有正常的11个基因组片段外，还含有一种RNA种类，其电泳迁移率略高于片段4。有限稀释传代使得能够分离出两个病毒克隆，这两个克隆可通过该基因组片段的电泳迁移率相互区分。讨论了这一发现对病毒行为以及通过RNA电泳比较轮状病毒的可能影响。
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