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[固定化肾上腺素对体力消耗恢复期大鼠心肌和骨骼肌中腺苷酸环化酶系统状态的影响]

[Effect of immobilized adrenaline on the state of the adenylate cyclase system in the cardiac and skeletal muscles of rats in the recuperative period after physical exertion].

作者信息

Kalinskiĭ M I, Kotsiuruba V N, Khalmuradov A G, Gubkina N I, Balakleevskiĭ A I

出版信息

Ukr Biokhim Zh (1978). 1984 Jan-Feb;56(1):52-7.

PMID:6324435
Abstract

It is shown that in the rehabilitation period after a single long physical load the adenylate cyclase activity and cAMP content in the skeletal muscle are low and normalize by the 48th and 36th h, respectively. These indices in the myocardium in the nearest rehabilitation period increase considerably, gradually normalizing by 24th and 48th h, respectively. Immobilized epinephrine accelerates normalization of the adenylate cyclase activity and cAMP content in the skeletal muscle and in myocardium in the rehabilitation period after physical load, the phosphodiesterase activity being unchanged.

摘要

结果表明,在单次长时间体力负荷后的康复期,骨骼肌中的腺苷酸环化酶活性和cAMP含量较低,分别在第48小时和第36小时恢复正常。在最近的康复期,心肌中的这些指标显著增加,分别在第24小时和第48小时逐渐恢复正常。固定化肾上腺素可加速体力负荷后康复期骨骼肌和心肌中腺苷酸环化酶活性和cAMP含量的恢复正常,而磷酸二酯酶活性不变。

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