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[大鼠个体发育过程中建立的条件反射系统的恢复以及促肾上腺皮质激素4-7的施用情况的改善]

[Improvement in the retrieval of a system of conditioned reflexes elaborated during rat ontogeny and administration of ACTH4-7].

作者信息

Tsitolovskaia L A

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1984 Jan-Feb;34(1):25-31.

PMID:6324508
Abstract

A chain of two conditioned reflexes was elaborated in prepubertal rats from 2 to 6 weeks of age. Then the nature of amnesia was studied after an interval of 2 weeks. The system of motor food-procuring conditioned reflexes, disturbed by the interval was reestablished almost completely by ACTH4-7 administration before testing. A deficit of retrieval is supposed to be the cause of amnesia in prepubertal rats. Analysis of erroneous movements during the restoration of motor skill showed that information less essential for food getting suffered to a greater extent and it was not restored by ACTH4-7 administration. The retrieval disturbance did not depend on the degree of stability of the motor skill and the age of its acquisition.

摘要

在2至6周龄的青春期前大鼠中建立了由两个条件反射组成的链。然后,在间隔2周后研究遗忘的性质。在测试前通过给予促肾上腺皮质激素4-7,几乎完全重建了因间隔期而受到干扰的运动性获取食物条件反射系统。推测检索缺陷是青春期前大鼠遗忘的原因。对运动技能恢复过程中错误动作的分析表明,对于获取食物不太重要的信息受到的影响更大,并且通过给予促肾上腺皮质激素4-7并未恢复。检索障碍并不取决于运动技能的稳定程度及其习得的年龄。

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