Abe S, Munakata M, Nishimura M, Tsuneta Y, Terai T, Nakano I, Ohsaki Y, Kawakami Y
Chest. 1984 May;85(5):650-5. doi: 10.1378/chest.85.5.650.
The intensity of gallium-67 scintiscans, lymphocyte counts in bronchoalveolar lavage fluid, and pathologic changes were studied in 26 patients with untreated pulmonary sarcoidosis. Noncaseating granulomas were recognized with significantly greater frequency in stage 2 (80 percent; 8/10 cases) than in stage 1 (43 percent; 6/14 cases). Alveolitis showed little relation to the roentgenographic stage. There was a strong correlation between the intensity of gallium uptake in pulmonary parenchyma and the detection rate of granuloma; however, the detection rate of alveolitis was not statistically different from the intensity of gallium uptake. A highly significant correlation was revealed between the lymphocyte counts in bronchoalveolar lavage fluid and the intensity of alveolitis. These observations suggest that the gallium uptake reflects mainly the presence of granuloma, and the lymphocyte count in bronchoalveolar lavage fluid reflects the intensity of alveolitis in patients with pulmonary sarcoidosis.
对26例未经治疗的肺结节病患者进行了镓-67闪烁扫描强度、支气管肺泡灌洗液中的淋巴细胞计数及病理改变的研究。非干酪性肉芽肿在2期（80%；8/10例）的检出频率显著高于1期（43%；6/14例）。肺泡炎与X线分期关系不大。肺实质镓摄取强度与肉芽肿检出率之间存在很强的相关性；然而，肺泡炎的检出率与镓摄取强度在统计学上无差异。支气管肺泡灌洗液中的淋巴细胞计数与肺泡炎强度之间显示出高度显著的相关性。这些观察结果表明，镓摄取主要反映肉芽肿的存在，而支气管肺泡灌洗液中的淋巴细胞计数反映肺结节病患者肺泡炎的强度。
