Bratcher R L, Kanik-Ennulat C L, Logue P J, Dunham P B
Immunol Commun. 1983;12(6):565-71. doi: 10.3109/08820138309025438.
Alloimmune antiserum against the L antigen of red cells from sheep of the LK phenotype is known to stimulate by several fold active Na/K transport in LK cells. We have shown that monomeric fragments, Fab1, of anti-L, as well as dimeric fragments, F(ab1)2, stimulate transport to the same extent as intact anti-L Ig. Special care was taken to obtain pure fragments. Two earlier reports on the effect of immunoglobulin fragments were contradictory.
已知针对LK表型绵羊红细胞L抗原的同种免疫抗血清可刺激LK细胞中活性钠/钾转运增加数倍。我们已经表明，抗L的单体片段Fab1以及二聚体片段F(ab1)2刺激转运的程度与完整的抗L Ig相同。我们特别注意获得纯片段。关于免疫球蛋白片段作用的两份早期报告相互矛盾。
