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促肾上腺皮质激素对泌乳山羊乳腺分泌的刺激作用与乳腺葡萄糖摄取增加无关。

Adrenocorticotrophic hormone stimulation of mammary secretion in lactating goats independent of increased mammary uptake of glucose.

作者信息

Stewart H J, Thompson G E

出版信息

J Endocrinol. 1984 May;101(2):203-11. doi: 10.1677/joe.0.1010203.

DOI:10.1677/joe.0.1010203
PMID:6325572
Abstract

The treatment of lactating goats with ACTH (single intramuscular injection) or cortisol (systemic infusion) resulted in an increase in milk yield and in the secretion of lactose, citrate and glucose into milk. The concentration of glucose in arterial plasma was also increased, resulting in a greater supply of glucose to the mammary gland. After ACTH treatment mammary uptake of glucose from the circulation did not increase and the balance between mammary uptake of glucose from blood and mammary output of glucose 'equivalents' into milk was significantly reduced. The results show that ACTH and cortisol can increase milk yield and lactose secretion by altering mammary metabolism of glucose.

摘要

用促肾上腺皮质激素(单次肌肉注射)或皮质醇(全身输注)处理泌乳山羊,可使产奶量增加,并使乳糖、柠檬酸盐和葡萄糖分泌到乳汁中。动脉血浆中的葡萄糖浓度也会升高,从而使乳腺获得更多的葡萄糖供应。促肾上腺皮质激素处理后,乳腺从循环中摄取的葡萄糖并未增加,乳腺从血液中摄取葡萄糖与乳腺向乳汁中输出“等效物”葡萄糖之间的平衡显著降低。结果表明,促肾上腺皮质激素和皮质醇可通过改变乳腺对葡萄糖的代谢来提高产奶量和乳糖分泌量。

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Adrenocorticotrophic hormone stimulation of mammary secretion in lactating goats independent of increased mammary uptake of glucose.促肾上腺皮质激素对泌乳山羊乳腺分泌的刺激作用与乳腺葡萄糖摄取增加无关。
J Endocrinol. 1984 May;101(2):203-11. doi: 10.1677/joe.0.1010203.
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Cold exposure and mammary glucose metabolism in the lactating goat.泌乳山羊的冷暴露与乳腺葡萄糖代谢
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Regulation of mammary glucose uptake in goats: role of mammary gland supply, insulin, IGF-1 and synthetic capacity.山羊乳腺葡萄糖摄取的调节:乳腺供应、胰岛素、胰岛素样生长因子-1及合成能力的作用
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Effect of acute stressors, adrenocorticotropic hormone administration, and cortisol release on milk yield, the expression of key genes, proliferation, and apoptosis in goat mammary epithelial cells.急性应激源、促肾上腺皮质激素给药和皮质醇释放对羊奶产量、关键基因表达、山羊乳腺上皮细胞增殖和凋亡的影响。
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Short-term lactation and mammary metabolism responses in lactating goats to graded removal of methionine from an intravenously infused complete amino acid mixture.静脉输注完全氨基酸混合物时,不同水平蛋氨酸去除对泌乳山羊短期泌乳和乳腺代谢的影响。
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