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关于一些非洲鼠科动物(啮齿目:鼠科)裂谷热的研究。

Studies on Rift Valley fever in some African murids (Rodentia: Muridae).

作者信息

Swanepoel R, Blackburn N K, Efstratiou S, Condy J B

出版信息

J Hyg (Lond). 1978 Apr;80(2):183-96. doi: 10.1017/s0022172400053535.

DOI:10.1017/s0022172400053535
PMID:632561
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2130003/
Abstract

Brains, spleens and livers of 2214 murids, 27 shrews and 7 dormice, trapped at 7 sites in Rhodesia, were tested in 277 pools for the presence of Rift Valley Fever virus. There were no isolations of Rift Valley Fever, but 69 isolations of an unidentified virus were obtained. Sixteen out of 867 sera had low-titre haemagglutination-inhibition activity against Rift Valley Fever antigen, but only one out of 1260 sera had neutralizing antibody. The evidence suggests that murids fail to encounter infection in nature and are unlikely to play a role in circulation and dissemination of Rift Valley Fever virus. Four out of seven widely distributed species of muried, Rhabdomys pumilio, Saccostomys campestris, Aethomys chrysophilus and Lemniscomys griselda, were shown to be capable of circulating amounts of virus likely to be infective for mosquitoes.

摘要

在罗德西亚7个地点捕获的2214只鼠科动物、27只鼩鼱和7只睡鼠的脑、脾和肝脏,被分成277组用于检测裂谷热病毒的存在。未分离到裂谷热病毒,但分离出69株未鉴定的病毒。867份血清中有16份对裂谷热抗原有低滴度血凝抑制活性,但1260份血清中只有1份有中和抗体。证据表明,鼠科动物在自然环境中未感染,不太可能在裂谷热病毒的循环和传播中起作用。在分布广泛的7种鼠科动物中,有4种,即黄毛鼠、平原囊鼠、金背小褐鼠和格氏水鼠,被证明能够携带可能感染蚊子的病毒量。

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本文引用的文献

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Amino acid metabolism in mammalian cell cultures.哺乳动物细胞培养中的氨基酸代谢
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Rift Valley fever in a wild field rat (Arvicanthis abyssinicus): a possible natural host.野生田鼠(阿比西尼亚草鼠)感染裂谷热:一种可能的自然宿主。
S Afr Med J. 1957 May 4;31(18):427-30.
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Relationship between plaque assay and the mouse assay for titrating Rift Valley fever virus.用于滴定裂谷热病毒的蚀斑试验与小鼠试验之间的关系。
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