氯尼达明单独及与其他化疗药物联合用于癌症患者的治疗。
Lonidamine alone and in combination with other chemotherapeutic agents in the treatment of cancer patients.
作者信息
Pacilio G, Carteni G, Biglietto M, De Cesare M
出版信息
Oncology. 1984;41 Suppl 1:108-12. doi: 10.1159/000225897.
PMID:6326014
Abstract
The tolerance and antitumor activity of Lonidamine administered alone and in combination with other anticancer agents were studied. Myalgia was the most frequent side effect; there were no changes in the hematological parameters attributable to Lonidamine administration. 1 partial response out of the 16 patients treated with Lonidamine alone was observed.
摘要
研究了单独使用氯尼达明以及将其与其他抗癌药物联合使用时的耐受性和抗肿瘤活性。肌痛是最常见的副作用；未观察到因使用氯尼达明而导致的血液学参数变化。在单独接受氯尼达明治疗的16例患者中，观察到1例部分缓解。
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