Harris D L, Garwood V A, Lowe P C, Hester P Y, Crittenden L B, Fadly A M
Poult Sci. 1984 Mar;63(3):401-13. doi: 10.3382/ps.0630401.
Data were collected on egg production, livability, lymphoid leukosis virus and antibody incidence, and hemagglutinin response to sheep red blood cells for slow- and fast-feathering female progeny from slow- and fast-feathering dams with known lymphoid leukosis virus infection status. Analyses of these results indicate that when the offspring or the dams are of the slow-feathering type, the offspring experience an increased rate of horizontal infection. This infection seemingly leads to an immunologically tolerant condition with an inability to produce specific lymphoid leukosis virus antibodies, thereby allowing the viremia to persist. This immunologically tolerant condition, which also occurs in the progeny of virus positive dams due to congenital transmission, is associated with depressed egg production performance. However, a hypothesized lack of immunological competence was not found in the hemagglutinin response to sheep red blood cells late in life. Our results suggest that fast-feathering progeny of slow-feathering dams may also be adversely influenced by increased congenital infection from their dams.
收集了已知感染淋巴白血病病毒的慢羽和快羽母本所产慢羽和快羽雌性后代的产蛋量、成活率、淋巴白血病病毒及抗体发生率，以及对绵羊红细胞的血凝素反应的数据。对这些结果的分析表明，当后代或母本为慢羽类型时，后代水平感染率会增加。这种感染似乎会导致免疫耐受状态，无法产生特异性淋巴白血病病毒抗体，从而使病毒血症持续存在。这种免疫耐受状态也会因先天性传播而发生在病毒阳性母本的后代中，与产蛋性能下降有关。然而，在生命后期对绵羊红细胞的血凝素反应中未发现假设的免疫能力缺乏。我们的结果表明，慢羽母本的快羽后代也可能因其母本先天性感染增加而受到不利影响。
