Cesaro P, Defer G, Barbizet J, Degos J D
Ann Med Interne (Paris). 1984;135(2):144-8.
The authors report two cases of Besnier -Boeck- Schaumann sarcoidosis with a neurological presentation. The first case was a 25 year old woman with a 5 year history of polyneuritis affecting the cranial and spinal nerves with very low nerve conduction times and without any detectable visceral disease. The diagnosis was made by distal bronchial biopsy. The second case was of an elderly man with tremor, difficulty in keeping his balance and deafness with chronic meningitis. The diagnosis was made by proximal bronchial biopsy, chest X-Ray showing a benign hilar lymphoma. In the first case, therapy comprised two three months courses of high dose intravenous steroids followed by oral corticosteroid therapy tailing off over three weeks. In the second case, the same intravenous steroid therapy was relayed by continuous oral steroids. The therapeutic effect was spectacular in the first case, but incomplete in the second, the intravenous steroids seeming to be more effective than the oral steroids.
作者报告了两例伴有神经症状的贝氏 - 伯克 - 绍曼结节病。第一例是一名25岁女性，患有5年多神经炎病史，累及颅神经和脊神经，神经传导时间极短，且未发现任何内脏疾病。诊断通过远端支气管活检做出。第二例是一名老年男性，有震颤、平衡困难和耳聋症状，伴有慢性脑膜炎。诊断通过近端支气管活检做出，胸部X光显示为良性肺门淋巴瘤。在第一例中，治疗包括两个为期三个月的高剂量静脉注射类固醇疗程，随后是为期三周逐渐减量的口服皮质类固醇治疗。在第二例中，同样的静脉注射类固醇治疗后接着持续口服类固醇。第一例的治疗效果显著，但第二例不完全，静脉注射类固醇似乎比口服类固醇更有效。
