Mascó D H, Carrer H F
Behav Brain Res. 1984 Mar;11(3):205-12. doi: 10.1016/0166-4328(84)90212-2.
In ovariectomized female rats primed with estradiol benzoate and progesterone, electrochemical stimulation of medial amygdaloid nucleus, anterior part ( AMEa ), increased lordotic frequency, but this effect was not found in rats with transection of the stria terminalis (ST) or the ventral amygdalofugal pathways ( VAF ). On the other hand, the decrease in lordotic frequency observed after stimulation of the posterior part of the lateral amygdaloid nucleus (ALp), persisted in animals with transection of the VAF , but was eliminated in animals with section of the ST. The effect of transecting these pathways on the multiunit and field responses evoked in the hypothalamic ventromedial nucleus (VMN) by stimulation of both amygdaloid nuclei was also studied. Responses evoked by AMEa stimulation were smaller or disappeared after lesion of either the ST or the VAF , but responses evoked by ALp stimulation were affected by lesion of the ST only. Findings are interpreted as suggesting that the ST conducts activity originating in AMEa and ALp which affects sexual receptivity in a complementary fashion, whereas VAF contains AMEa originated fibers whose activation increase receptivity. These behavioral effects may be the consequence of modulatory action on VMN neuronal activity.
在接受苯甲酸雌二醇和孕酮预处理的去卵巢雌性大鼠中，对杏仁核内侧核前部（AMEa）进行电化学刺激会增加脊柱前凸频率，但在终纹（ST）或腹侧杏仁体传出通路（VAF）横断的大鼠中未发现这种效应。另一方面，刺激杏仁核外侧核后部（ALp）后观察到的脊柱前凸频率降低，在VAF横断的动物中持续存在，但在ST横断的动物中消失。还研究了横断这些通路对刺激两个杏仁核在下丘脑腹内侧核（VMN）诱发的多单位和场反应的影响。AMEa刺激诱发的反应在ST或VAF损伤后变小或消失，但ALp刺激诱发的反应仅受ST损伤的影响。研究结果表明，ST传导起源于AMEa和ALp的活动，它们以互补方式影响性接受能力，而VAF包含起源于AMEa的纤维，其激活会增加接受能力。这些行为效应可能是对VMN神经元活动进行调节作用的结果。
