Hof L, Csiza C K, Dentinger M P, Barron K D
J Neurochem. 1984 Jun;42(6):1767-70. doi: 10.1111/j.1471-4159.1984.tb12770.x.
2',3'-Cyclic nucleotide 3'-phosphodiesterase activity was examined in brains and spinal cords of normal and myelin-deficient Wistar rats. While the activity in normal brains increased from 0.2 mumol/min/mg protein (units) at 6-10 days to 3.5 units at 25 days of postnatal age, the activity in the myelin-deficient rat remained at 0.2-0.3 units over the same period. In spinal cord, the normal activities were 5.7 and 10.9 units at 12 and 20 days, respectively, whereas they declined in the myelin-deficient rat from 1.06 to 0.79 units for the same age points. 5'-Nucleotidase activities in brain and spinal cord were normal in the myelin deficient rat at both ages.
在正常和髓磷脂缺乏的Wistar大鼠的脑和脊髓中检测了2',3'-环核苷酸3'-磷酸二酯酶活性。正常脑内的活性在出生后6 - 10天从0.2微摩尔/分钟/毫克蛋白质（单位）增加到25天时的3.5单位，而在同一时期，髓磷脂缺乏大鼠的活性保持在0.2 - 0.3单位。在脊髓中，正常活性在12天和20天时分别为5.7和10.9单位，而在髓磷脂缺乏大鼠中，相同年龄点的活性从1.06单位下降到0.79单位。在两个年龄段，髓磷脂缺乏大鼠脑和脊髓中的5'-核苷酸酶活性均正常。
