Perry R P, Jacobsen E S
J Rheumatol. 1984 Apr;11(2):233-4.
We describe a case with neurologic disease manifested as encephalopathy, generalized muscle fasciculations, and peripheral neuropathy occurring in a patient treated with therapeutic doses of gold for presumed rheumatoid arthritis. The illness remitted promptly during chelation therapy with dimercaprol (BAL). A review of the limited experience in the literature with the central nervous system toxicity of gold is given.
我们描述了一例患有神经系统疾病的病例,该患者因疑似类风湿性关节炎接受治疗剂量的金制剂治疗后,出现脑病、全身性肌肉束颤和周围神经病变。在使用二巯丙醇(BAL)进行螯合治疗期间,病情迅速缓解。本文还回顾了文献中关于金制剂中枢神经系统毒性的有限经验。