Transient tension development induced by silver ion in Ca2+ -channel blocked skeletal muscle fibers.

Ag+ produced two different types of transient tension development in single frog toe muscle fibers in which the Ca2+ channel had been blocked by pretreatment with 2mM Co2+. These contractions were never observed in detubulated fibers, indicating that the Ag+ -induced contraction is produced through Ca2+ channels located on the T-tubular membrane.