Salerno T A, Munro D D, Little J R
J Neurosurg. 1978 Mar;48(3):350-4. doi: 10.3171/jns.1978.48.3.0350.
Twenty-three patients with bronchogenic carcinoma and a brain metastasis had their primary and secondary tumors treated surgically. The 10 men and 13 women had an average age of 52 years. Fifteen patients presented with a lesion of the lung and eight patients presented initially with neurological findings of an intracranial mass lesion. The most common histological type of tumor was adenocarcinoma (48%), followed by squamous cell carcinoma, undifferentiated small cell carcinoma, and bronchoalveolar carcinoma. Twelve patients (52%) had a poor result and died during the first six months. Surgery appeared to improve short-term survival in six patients (26%). Five patients (22%) had a good result and lived longer than 2 years without significant neurological deficit. Three patients (13%) are alive 10 or more years following surgery.
23例患有支气管源性癌并伴有脑转移的患者接受了原发肿瘤和继发肿瘤的手术治疗。其中10名男性和13名女性，平均年龄为52岁。15例患者最初表现为肺部病变，8例患者最初表现为颅内肿块病变的神经学症状。最常见的肿瘤组织学类型是腺癌（48%），其次是鳞状细胞癌、未分化小细胞癌和细支气管肺泡癌。12例患者（52%）预后不良，在头6个月内死亡。手术似乎使6例患者（26%）的短期生存率得到改善。5例患者（22%）预后良好，存活超过2年且无明显神经功能缺损。3例患者（13%）术后存活10年或更长时间。
