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使用抗前列腺酸性磷酸酶的放射性标记抗体进行前列腺癌成像的临床研究。

Clinical studies of prostatic cancer imaging with radiolabeled antibodies against prostatic acid phosphatase.

作者信息

Goldenberg D M, DeLand F H

出版信息

Urol Clin North Am. 1984 May;11(2):277-81.

PMID:6328719
Abstract

Conventional antibodies against prostatic acid phosphatase, labeled with iodine-131, have been administered to patients with prostatic carcinoma for the external scintigraphic imaging of tumors containing prostatic acid phosphatase (radioimmunodetection). The method has been found to be safe and reliable for imaging of primary tumors and non-bone metastases, even differentiating between lung tumors of prostatic and pulmonary origin.

摘要

已将用碘 - 131标记的抗前列腺酸性磷酸酶的传统抗体给予前列腺癌患者,用于对含有前列腺酸性磷酸酶的肿瘤进行体外闪烁成像(放射免疫检测)。已发现该方法对于原发性肿瘤和非骨转移灶的成像安全可靠,甚至能够区分前列腺来源和肺来源的肺部肿瘤。

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