Krishnamurthy G T
J Nucl Med. 1978 Mar;19(3):284-6.
The incidence of allergic reactions to bovine TSH and its relation to dose have been studied in 42 patients with thyroid cancer who had total ablation of functioning thyroidal tissue and have been followed prospectively for up to 25 yr. Of these patients, 43% showed an allergic reaction to bovine TSH. The remaining 57% have shown no reaction, even though they have received cumulative TSH doses larger than those who did show a reaction. The reaction rate is linear up to a cumulative dose of 150 units and is not dose-related therafter.
在42例甲状腺癌患者中，研究了对牛促甲状腺素（TSH）过敏反应的发生率及其与剂量的关系。这些患者功能性甲状腺组织已全部切除，并进行了长达25年的前瞻性随访。在这些患者中，43%对牛TSH有过敏反应。其余57%未出现反应，尽管他们接受的TSH累积剂量大于出现反应的患者。反应率在累积剂量达150单位之前呈线性，之后与剂量无关。
