Buño W, Fuentes J
Brain Res. 1984 Jun 11;303(1):101-7. doi: 10.1016/0006-8993(84)90215-4.
The effects were examined of brief lengthening perturbations of different amplitudes on the pacemaker activity of the slowly adapting stretch receptor organ of crayfish. The analysis indicates that perturbation effects: (i) when elicited by low amplitudes, depend on the delivery time (or phase) of the perturbation relative to the last spike, while those evoked by larger amplitudes are phase-independent; (ii) tend to decrease, below the value of the natural interspike interval or pacemaker period, the interval at which the perturbation is delivered, anticipating the occurrence of the next spike; (iii) which follow the first poststimulus spike consist of phase-dependent lengthenings of interspike intervals which are greater for the first and decrease gradually in length in the following post-perturbation intervals; (iv) are gradually compensated because the pre-perturbation phase tends to be recovered in the interspike intervals following the perturbation and spikes gradually tend to occur closer to the instants when they would have fired without the perturbation. Although other models may explain the above behavior, phase compensation suggests strongly that at least two oscillators (i.e., an unperturbable oscillator and a stimulus sensitive one) underlie the pacemaker activity of the slowly adapting organ.
研究了不同幅度的短暂延长扰动对小龙虾缓慢适应牵张感受器器官起搏活动的影响。分析表明，扰动效应：(i) 当由低幅度引发时，取决于扰动相对于最后一个尖峰的发放时间（或相位），而由较大幅度引发的那些效应则与相位无关；(ii) 倾向于在低于自然峰峰间隔或起搏周期的值时，缩短扰动发放的间隔，预期下一个尖峰的出现；(iii) 在刺激后的第一个尖峰之后，由峰峰间隔的相位依赖性延长组成，第一个间隔的延长更大，并且在随后的扰动后间隔中长度逐渐减小；(iv) 会逐渐得到补偿，因为在扰动后的峰峰间隔中，扰动前的相位倾向于恢复，并且尖峰逐渐倾向于在没有扰动时本来会发放的时刻附近出现。虽然其他模型可能解释上述行为，但相位补偿强烈表明，至少有两个振荡器（即一个不受扰动的振荡器和一个对刺激敏感的振荡器）是缓慢适应器官起搏活动的基础。
