雅巴猴肿瘤病毒在食蟹猴肾细胞系中的形态发生

The morphogenesis of Yaba monkey tumor virus in a cynomolgus monkey kidney cell line.

作者信息

Rouhandeh H, Vafai A, Kilpatrick D

出版信息

J Ultrastruct Res. 1984 Jan;86(1):100-5. doi: 10.1016/s0022-5320(84)90100-x.

Abstract

The morphogenesis of Yaba monkey tumor virus (YMTV) was investigated in a cynomolgus monkey kidney cell line. YMTV has been shown to grow less rapidly in high-passage cells (i.e., 65 passages) than in low-passage cells (i.e., between 30 and 60 passages). This prolonged growth cycle in high-passage cells allows for a more detailed analysis of the events in morphogenesis. Samples of YMTV-infected cells were prepared for analysis at 2, 3, 4, and 5 days postinfection. At least 12 "stages" of virus morphogenesis can be identified.

摘要

在食蟹猴肾细胞系中研究了雅巴猴肿瘤病毒（YMTV）的形态发生。已证明YMTV在高代细胞（即65代）中生长速度比低代细胞（即30至60代）慢。高代细胞中这种延长的生长周期允许对形态发生过程中的事件进行更详细的分析。在感染后2、3、4和5天制备YMTV感染细胞的样本用于分析。病毒形态发生至少可识别出12个“阶段”。