Leroy D, Michel M, Vion M, Mahoudeau J, Deschamps P
Presse Med. 1984 Jun 16;13(25):1559-63.
A case of monilial granuloma of 12 years duration is being successfully treated with ketoconazole administered orally in doses of 200 mg per day. Trush, onyxis and keratotic granulomatous lesions of the face and hands have dramatically regressed. In view of persistent anomalies of cellular immunity and complete deficiency in serum and salivary IgA, treatment with ketoconazole at the same dosage level has now been continuously pursued for 30 months without any evidence of toxicity.
一例病程长达12年的念珠菌性肉芽肿，正通过口服酮康唑成功治疗，剂量为每日200毫克。面部和手部的鹅口疮、甲癣和角化性肉芽肿性病变已显著消退。鉴于细胞免疫持续异常以及血清和唾液IgA完全缺乏，目前已持续以相同剂量水平使用酮康唑治疗30个月，未出现任何毒性迹象。
