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使用鱿鱼三阶空间梯度仪测量大脑磁场。

The use of a squid third order spatial gradiometer to measure magnetic fields of the brain.

作者信息

Weinberg H, Brickett P A, Vrba J, Fife A A, Burbank M B

出版信息

Ann N Y Acad Sci. 1984;425:743-52. doi: 10.1111/j.1749-6632.1984.tb23597.x.

Abstract

It appears to be clear from the results that the third order gradiometer is able to detect small biomagnetic signals from the brain which are related to evoked potentials and spontaneous electrical activity. The instrument operates reasonably well within a noisy environment, however further development is necessary to balance the first gradient. We intend to pursue this direction with software systems. Some of the data presented suggest that components of MEG evoked activity may change independently of EEG. One interpretation which may derive from this is that the same current dipoles are probably not responsible for the entire configuration of evoked fields. This interpretation is consistent with EEG evidence which indicates that analogous components in the evoked potential may vary independently as a function of stimulus parameters and information processing. Perhaps a model of magnetic dipoles due to small current loops would be more compatible with the electrophysiological data.

摘要

从结果来看似乎很清楚,三阶梯度仪能够检测到来自大脑的与诱发电位和自发脑电活动相关的小生物磁信号。该仪器在嘈杂环境中运行得还算不错,不过要平衡第一梯度还需要进一步改进。我们打算通过软件系统朝着这个方向努力。所呈现的一些数据表明,脑磁图诱发活动的成分可能独立于脑电图而变化。由此可能得出的一种解释是,诱发场的整个构型可能并非由相同的电流偶极子产生。这种解释与脑电图证据一致,脑电图证据表明诱发电位中的类似成分可能会随着刺激参数和信息处理而独立变化。也许由小电流环引起的磁偶极子模型会与电生理数据更相符。

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