Aghajanian G K, Lakoski J M
Brain Res. 1984 Jul 2;305(1):181-5. doi: 10.1016/0006-8993(84)91137-5.
Serotonin and LSD hyperpolarized serotonergic dorsal raphe neurons in rat midbrain slices; the hyperpolarizations were accompanied by a decrease in input resistance, suggesting an increase in potassium conductance as one possible mechanism. Reversal potentials for serotonin and LSD-induced hyperpolarizations showed a shift of approximately 18 mV for a two-fold change in extracellular potassium concentration; this shift was close to that predicted by the Nernst equation for a potassium-dependent conductance.
血清素和麦角酸二乙酰胺（LSD）使大鼠中脑切片中的血清素能背缝核神经元超极化；这种超极化伴随着输入电阻的降低，这表明钾电导增加是一种可能的机制。血清素和LSD诱导的超极化的反转电位显示，细胞外钾浓度两倍变化时，电位偏移约18 mV；这种偏移接近能斯特方程预测的钾依赖性电导的偏移。
