Kolker I I, Gel'fand V B, Nikolaev G V
Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(5):675-9.
The urgent questions of neuropsychic disorders related to thermal lesions are discussed on the basis of an analysis of the literature data and the results of the authors' long-term studies. It is shown that all these disturbances are formed in patients with deep burns affecting over 15% of the body's surface in the presence of marked disturbances of all links of the systemic anti-infection defence, the latter being conducive to the generalization of the infectious process. Thus, these pronounced disorders of the immunologic mechanisms of homeostasis are responsible for the background against which those severely burned develop the organic neuropsychopathological syndrome, burn-associated encephalopathy, which persists for a long time after the trauma.
基于对文献数据的分析和作者长期研究的结果，讨论了与热损伤相关的神经精神障碍的紧迫问题。结果表明，所有这些障碍都在全身抗感染防御各环节存在明显紊乱的情况下，发生于体表烧伤面积超过15%的深度烧伤患者中，而全身抗感染防御紊乱有利于感染过程的扩散。因此，这些内环境稳态免疫机制的明显紊乱是严重烧伤患者发生有机神经精神病理综合征——烧伤相关性脑病的背景原因，该综合征在创伤后会长期持续存在。
