Shmatko V G, Kvetkova E A, Ereniev S I
Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(6):814-9.
In 51 epileptic patients with frequent attacks, the clinical manifestations were correlated with some parameters of immune responsiveness. The authors determined the content of plasma globulins of the main classes, cerebral antibodies, T and B lymphocytes, the rate of the inhibition of the leukocyte migration with respect to the cerebral antigen. Epilepsy was shown to run its course in the presence of immune responsiveness depression. A certain relationship existed between the duration of the disease, the endogenic factors, the nature of fits and some immunologic indices. With the development of the disease, the initial deficiency of the B lymphocyte immunity was coupled with the progressive dysfunction of the T lymphocyte immunity.
在51例癫痫频繁发作患者中，临床表现与一些免疫反应参数相关。作者测定了主要类别的血浆球蛋白含量、脑抗体、T淋巴细胞和B淋巴细胞，以及白细胞对脑抗原迁移的抑制率。结果显示，癫痫在免疫反应性降低的情况下发生发展。疾病持续时间、内源性因素、发作性质与一些免疫学指标之间存在一定关系。随着疾病的发展，最初的B淋巴细胞免疫缺陷与T淋巴细胞免疫的进行性功能障碍并存。
