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颅内表皮样囊肿继发复发性无菌性脑膜炎

Recurrent aseptic meningitis secondary to intracranial epidermoids.

作者信息

Becker W J, Watters G V, de Chadarevian J P, Vanasse M

出版信息

Can J Neurol Sci. 1984 Aug;11(3):387-9. doi: 10.1017/s0317167100045777.

DOI:10.1017/s0317167100045777
PMID:6331872
Abstract

Two patients with recurrent aseptic meningitis are reported. Intracranial epidermoid tumors were eventually found in both patients. CSF changes in our first case with an epidermoid tumor were similar to those reported in Mollaret's meningitis, with an initial polymorphonuclear pleocytosis early in each attack, followed by a lymphocytic predominance several days later. Large cells which proved to be macrophages were also seen in the CSF of this patient. Both patients had meningitis attacks for several years before the underlying epidermoid tumor was found. Mollaret's meningitis remains a diagnosis of exclusion. These patients should remain tumor suspects for many years and deserve careful and repeated investigation.

摘要

报告了两名复发性无菌性脑膜炎患者。最终在两名患者中均发现了颅内表皮样肿瘤。我们第一例患有表皮样肿瘤患者的脑脊液变化与莫拉雷脑膜炎中报道的相似,每次发作初期有中性粒细胞增多,数天后淋巴细胞占优势。在该患者的脑脊液中还可见到被证实为巨噬细胞的大细胞。两名患者在发现潜在的表皮样肿瘤之前都有多年的脑膜炎发作史。莫拉雷脑膜炎仍然是一种排除性诊断。这些患者多年来都应被怀疑有肿瘤,值得仔细反复检查。

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1
Recurrent aseptic meningitis secondary to intracranial epidermoids.颅内表皮样囊肿继发复发性无菌性脑膜炎
Can J Neurol Sci. 1984 Aug;11(3):387-9. doi: 10.1017/s0317167100045777.
2
Mollaret's recurrent aseptic meningitis and cerebral epidermoid cyst.
Pediatr Neurol. 1998 Feb;18(2):156-9. doi: 10.1016/s0887-8994(97)00156-2.
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Mollaret's recurrent aseptic meningitis: relationship to epidermoid cysts. Light microscopic and ultrastructural cytological studies of the cerebrospinal fluid.莫拉雷复发性无菌性脑膜炎:与表皮样囊肿的关系。脑脊液的光镜和超微结构细胞学研究
J Neuropathol Exp Neurol. 1980 Nov;39(6):661-9.
4
[Dermoid cysts of the posterior cerebral fossa in children revealed by recurrent aseptic meningitis: Report of two cases and a review of the literature].
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[Recurrent aseptic meningitis in periodic disease or Mollaret's meningitis?].[周期性疾病中的复发性无菌性脑膜炎还是莫拉雷脑膜炎?]
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Mollaret's meningitis: an unusual disease with a characteristic presentation.莫拉雷脑膜炎:一种具有特征性表现的罕见疾病。
Am J Med Sci. 1984 Jan-Feb;287(1):52-3. doi: 10.1097/00000441-198401000-00015.
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Chemical meningitis in ruptured intracranial dermoid. Case report and review of the literature.颅内皮样囊肿破裂所致化学性脑膜炎。病例报告及文献复习。
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[Recurrent aseptic meningitis caused by rupture of a pineal cyst].
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Recurrent aseptic meningitis secondary to intracranial epidermoid cyst and Mollaret's meningitis: two distinct entities or a single disease? A case report and a nosologic discussion.颅内表皮样囊肿继发复发性无菌性脑膜炎与莫拉雷脑膜炎:两种不同的疾病实体还是单一疾病?病例报告及疾病分类学讨论
Am J Med. 1990 Dec;89(6):807-10. doi: 10.1016/0002-9343(90)90226-4.
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A case of recurrent benign lymphocytic (Mollaret's) meningitis and review of the literature.复发性良性淋巴细胞性(Mollaret)脑膜炎 1 例并文献复习。
J Infect Public Health. 2010 Dec;3(4):192-5. doi: 10.1016/j.jiph.2010.09.006. Epub 2010 Nov 9.

引用本文的文献

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Atypical spinal endodermal cyst presenting with contralateral C2 neuralgia and aseptic meningitis.表现为对侧C2神经痛和无菌性脑膜炎的非典型脊髓内胚层囊肿。
Radiol Case Rep. 2019 Feb 27;14(5):561-564. doi: 10.1016/j.radcr.2019.02.013. eCollection 2019 May.
3
Mollaret's meningitis.
莫拉雷脑膜炎
West J Med. 1994 May;160(5):459-62.
4
Post-operative aseptic meningitis.
Acta Neurochir (Wien). 1987;89(3-4):112-6. doi: 10.1007/BF01560375.
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Cranial and spinal tumors with meningitic onset.伴有脑膜炎起病的颅脑和脊髓肿瘤。
Ital J Neurol Sci. 1990 Apr;11(2):145-51. doi: 10.1007/BF02335557.