在体外超灌注前列腺素 F-2α、促黄体生成素和雌二醇时，早期妊娠母猪黄体的孕酮分泌情况。
Progesterone secretion by the corpus luteum of the early pregnant pig during superfusion in vitro with PGF-2alpha, LH and oestradiol.
作者信息
Watson J, Maule Walker F M
出版信息
J Reprod Fertil. 1978 Mar;52(2):209-12. doi: 10.1530/jrf.0.0520209.
PMID:633204
Abstract
Corpora lutea obtained from pregnant sows (Days 18-22) were superfused in vitro for 2-4 h with PGF-2alpha and for 3 h with LH or oestradiol or combinations of PGF-2alpha with LH or oestradiol. LH but not oestradiol stimulated progesterone secretion while superfusion for a minimum of 3 h with PGF-2alpha caused an irreversible decrease in progesterone secretion. LH and PGF-2alpha were mutually antagonistic while oestradiol did not inhibit the luteolytic action of PGF-2alpha.
摘要
从妊娠母猪（第18 - 22天）获取的黄体在体外进行2 - 4小时的前列腺素F2α（PGF - 2α）灌注，并分别与促黄体生成素（LH）、雌二醇单独或与PGF - 2α联合进行3小时灌注。LH而非雌二醇刺激孕酮分泌，而至少3小时的PGF - 2α灌注会导致孕酮分泌不可逆减少。LH与PGF - 2α相互拮抗，而雌二醇不抑制PGF - 2α的溶黄体作用。
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