犬类尿路感染：体外抗菌药敏试验结果与氨苄西林或甲氧苄啶-磺胺口服治疗反应的比较。

Canine urinary tract infections: a comparison of in vitro antimicrobial susceptibility test results and response to oral therapy with ampicillin or with trimethoprim-sulfa.

作者信息

Ling G V, Rohrich P J, Ruby A L, Johnson D L, Jang S S

出版信息

J Am Vet Med Assoc. 1984 Aug 1;185(3):277-81.

Abstract

In vitro susceptibility testing correctly predicted the outcome of ampicillin therapy in all 56 urinary tract infections (UTI) caused by coagulase-positive staphylococci (Staphylococcus aureus and S intermedius), in all 26 UTI caused by Proteus mirabilis, in 38 of 44 UTI caused by Escherichia coli, in 29 of 31 UTI caused by Streptococcus spp, in 8 of 10 UTI caused by Klebsiella pneumoniae, and in 16 of 20 UTI caused by other bacterial species. Thus, 173 of 187 (92.5%) isolates responded to ampicillin therapy in a manner predicted by in vitro susceptibility test results. In vitro susceptibility testing correctly predicted the outcome of therapy with trimethoprim-sulfa in 119 of 138 UTI caused by Escherichia coli, in 33 of 45 UTI caused by Klebsiella pneumoniae, in 38 of 43 UTI caused by Proteus mirabilis, in 21 of 25 UTI caused by Streptococcus spp, in 9 of 11 UTI caused by coagulase-positive staphylococci, and in 19 of 21 UTI caused by other bacterial species. Thus, 239 of 283 (84%) isolates responded to trimethoprim-sulfa therapy in a manner predicted by in vitro susceptibility test results.

摘要

体外药敏试验正确预测了所有56例由凝固酶阳性葡萄球菌（金黄色葡萄球菌和中间葡萄球菌）引起的尿路感染（UTI）、所有26例由奇异变形杆菌引起的UTI、44例由大肠杆菌引起的UTI中的38例、31例由链球菌属引起的UTI中的29例、10例由肺炎克雷伯菌引起的UTI中的8例以及20例由其他细菌种类引起的UTI中的16例氨苄西林治疗的结果。因此，187株分离菌中有173株（92.5%）对氨苄西林治疗的反应与体外药敏试验结果预测的一致。体外药敏试验正确预测了138例由大肠杆菌引起的UTI中的119例、45例由肺炎克雷伯菌引起的UTI中的33例、43例由奇异变形杆菌引起的UTI中的38例、25例由链球菌属引起的UTI中的21例、11例由凝固酶阳性葡萄球菌引起的UTI中的9例以及21例由其他细菌种类引起的UTI中的19例甲氧苄啶-磺胺治疗的结果。因此，283株分离菌中有239株（84%）对甲氧苄啶-磺胺治疗的反应与体外药敏试验结果预测的一致。