Webb W R, Gamsu G, Stark D D, Moon K L, Moore E H
AJR Am J Roentgenol. 1984 Oct;143(4):723-7. doi: 10.2214/ajr.143.4.723.
Ten patients having a mediastinal tumor were studied with magnetic resonance imaging (MRI) using from two to four imaging sequences. Seven had bronchial carcinoma and three had benign lesions. The sequences included the spin-echo technique with repetition time (TR) values of 0.5, 1.0, and 2.0 sec and echo time (TE) values of 28 and 56 msec, and the inversion-recovery technique. The signal-intensity ratios of the mediastinal mass and mediastinal fat, which are a measure of image contrast, were compared for the different imaging sequences. Also signal-to-noise ratios were measured relative to both mediastinal fat and mediastinal mass. With spin-echo imaging, decreasing the TR value resulted in an increase in mass/fat contrast in all patients, making the masses easier to detect, but this also resulted in decreased signal-to-noise ratios. Inversion-recovery imaging with the sequence used resulted in a greatly increased mass/fat contrast, because of a relative decrease in signal from the mass. However, in two of four patients studied with this technique, the mass was so low in intensity that it could not be distinguished from the trachea or mediastinal vessels, and in one of these four, a lung nodule was also invisible. Spin-echo imaging with both short and long TR values provides good tissue contrast and good signal-to-noise ratios.
对10例患有纵隔肿瘤的患者进行了磁共振成像(MRI)研究,使用了两到四个成像序列。其中7例患有支气管癌,3例患有良性病变。这些序列包括重复时间(TR)值为0.5、1.0和2.0秒且回波时间(TE)值为28和56毫秒的自旋回波技术,以及反转恢复技术。针对不同的成像序列,比较了作为图像对比度指标的纵隔肿块与纵隔脂肪的信号强度比。还相对于纵隔脂肪和纵隔肿块测量了信噪比。在自旋回波成像中,降低TR值会导致所有患者的肿块/脂肪对比度增加,使肿块更易于检测,但这也会导致信噪比降低。使用该序列的反转恢复成像导致肿块/脂肪对比度大幅增加,这是由于肿块信号相对降低所致。然而,在使用该技术研究的4例患者中,有2例肿块的信号强度很低,以至于无法与气管或纵隔血管区分开来,在这4例患者中的1例中,肺部结节也不可见。具有短TR值和长TR值的自旋回波成像提供了良好的组织对比度和良好的信噪比。