Duray P H, Marcal J M, LiVolsi V A, Fisher R, Scholhamer C, Brand M H
J Clin Gastroenterol. 1984 Aug;6(4):311-9. doi: 10.1097/00004836-198408000-00001.
The predominant site of bleeding intestinal angiodysplasia in elderly patients will be the cecum or ascending colon, but recent experience in the Yale-Affiliated Gastroenterology Program in 1 year indicates that elderly patients may have bleeding acquired angiodysplasia (AD) confined to the small intestine only. A review of the literature confirms that symptomatic small intestinal AD is infrequent and occurs at an average age of 32 years in some series. Five patients with symptomatic small intestinal AD diagnosed during 1981 at Yale were older, with an average of 62 years. Three of the five cases (all female) had lesions in the duodenum, with two (males) having lesions in the ileum. Noncolonic AD in the elderly may be acquired during life, as in the classic situation in the right colon, but may be difficult to distinguish clinically and pathologically from the vascular lesions of hereditary hemorrhagic telangiectasia.
老年患者肠道血管发育异常出血的主要部位是盲肠或升结肠，但耶鲁附属胃肠病学项目近一年的经验表明，老年患者可能仅在小肠出现获得性血管发育异常（AD）出血。文献综述证实，有症状的小肠AD并不常见，在一些系列研究中平均发病年龄为32岁。1981年在耶鲁诊断出的5例有症状的小肠AD患者年龄较大，平均年龄为62岁。5例中有3例（均为女性）病变位于十二指肠，2例（男性）病变位于回肠。老年人的非结肠AD可能是在生活中获得的，就像右结肠的典型情况一样，但在临床和病理上可能难以与遗传性出血性毛细血管扩张症的血管病变区分开来。
