Khil'ko V A, Artemov I V, Khlunovskiĭ A N
Zh Vopr Neirokhir Im N N Burdenko. 1984 Jul-Aug(4):35-9.
Analysis of 445 fatal cases among which 21 were marked by profuse gastroduodenal hemorrhage showed that this complication develops in ulceration of the mucous-membrane in the upper parts of the digestive tract and occurs most frequently in affection of the hypothalamic region and brain stem. Gastrointestinal hemorrhages are caused to a certain measure by medication with massive doses of corticosteroids in the stage of tension of the general adaptation syndrome, hypoxia of the mucous membrane, azotemia, and other disorders of homeostasis. Gastrointestinal hemorrhages greatly aggravate the condition of neurosurgical patients, they are diagnosed with difficulty, and their prevention calls for a complex approach.
对445例死亡病例的分析显示，其中21例以胃十二指肠大出血为特征，这种并发症发生在消化道上部黏膜溃疡，最常发生在下丘脑区域和脑干病变时。在全身适应综合征紧张阶段大剂量使用皮质类固醇药物、黏膜缺氧、氮质血症和其他内稳态紊乱在一定程度上导致了胃肠道出血。胃肠道出血极大地加重了神经外科患者的病情，诊断困难，其预防需要综合方法。
