γ射线辐照对体外微管组装的影响。

Effect of gamma-irradiation on microtubule assembly in vitro.

作者信息

Gal V, Trajković D

出版信息

Int J Radiat Biol Relat Stud Phys Chem Med. 1984 Oct;46(4):435-42. doi: 10.1080/09553008414551631.

Abstract

Microtubular protein was exposed to gamma-radiation from 500 to 1000 Gy, Within that dose range its polymerization ability was decreased by 20-60 per cent when samples were irradiated in assembled state, and by 40-75 per cent when irradiated in unassembled state. Microtubules assembled from irradiated subunits were shorter and of more uniform lengths than control microtubules. For the dose of 1000 Gy the mean length and its standard deviation were reduced to about one-half of the values of the control.

摘要

微管蛋白受到500至1000戈瑞的γ射线辐射。在该剂量范围内，当样品处于组装状态下进行辐照时，其聚合能力下降了20%至60%；而在未组装状态下辐照时，聚合能力下降了40%至75%。由受辐照亚基组装而成的微管比对照微管更短且长度更均匀。对于1000戈瑞的剂量，平均长度及其标准偏差降至对照值的约二分之一。