大鼠对[14C]青霉酸的胆汁排泄。
Biliary excretion of [14C]penicillic acid by rats.
作者信息
Park D L, Brouwer E, Heath J L
出版信息
J Toxicol Environ Health. 1978 Jan;4(1):9-13. doi: 10.1080/15287397809529639.
PMID:633414
Abstract
Adult male rats were given [14C]penicillic acid by oral intubation, and the biliary excretion of the compound was monitored. The significance of bile as an excretory route was confirmed and compared by using open and recycle cannulation of the bile duct. The biological half-retention life of [14C]penicillic acid in the bile was 3.63 h.
摘要
成年雄性大鼠经口插管给予[14C]青霉酸，并监测该化合物的胆汁排泄情况。通过使用胆管开放插管和循环插管，证实并比较了胆汁作为排泄途径的重要性。[14C]青霉酸在胆汁中的生物半潴留期为3.63小时。
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