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澳大利亚和美国的血压水平与脑血管疾病死亡率

Blood pressure levels and mortality from cerebrovascular disease in Australia and the United States.

作者信息

MacMahon S W, Leeder S R

出版信息

Am J Epidemiol. 1984 Dec;120(6):865-75. doi: 10.1093/oxfordjournals.aje.a113958.

DOI:10.1093/oxfordjournals.aje.a113958
PMID:6334440
Abstract

Blood pressure distributions were compared in two groups of subjects aged 25-64 years surveyed in the Risk Factor Prevalence Study in Australia and the Lipid Research Clinics Prevalence Study in North America. In men and women of all age groups, systolic and diastolic blood pressures were greater in the Australian study than in the North American study; the prevalence of hypertension was almost twice as great in the Australian study. The proportion of the total population receiving antihypertensive treatment was also greater in the Australian study. However, among those subjects classified as hypertensive, a greater proportion were receiving treatment in the North American study. The differences in blood pressure levels did not appear to be due to differences in body mass index. In men, possible differences in alcohol consumption could account for some of the difference in blood pressure levels but data from the Australian study suggest that such differences could only account for a small proportion of the difference in prevalence of hypertension. The higher blood pressures and greater prevalence of hypertension in the Australian study were consistent with a 40-55% greater mortality from cerebrovascular disease in Australia than the United States (1968-1977), observed in both men and women from age 45 years onwards. In Australia in 1978, this difference accounted for over 4,200 excess deaths (4% of annual mortality), 600 of which occurred in men and women below the age of 65 years. Mortality from other hypertensive diseases was also greater in Australia than in the United States, which gives further support to the suggestion that population blood pressures and hypertension-related mortality are greater in Australia than they are in the United States.

摘要

在澳大利亚开展的危险因素患病率研究和北美脂质研究诊所患病率研究中,对两组年龄在25至64岁的受试者的血压分布情况进行了比较。在所有年龄组的男性和女性中,澳大利亚研究中的收缩压和舒张压均高于北美研究;澳大利亚研究中高血压的患病率几乎是北美研究的两倍。澳大利亚研究中接受抗高血压治疗的总人口比例也更高。然而,在那些被归类为高血压患者的受试者中,北美研究中有更大比例的人正在接受治疗。血压水平的差异似乎并非由于体重指数的差异所致。在男性中,饮酒量的可能差异可以解释血压水平差异的一部分,但澳大利亚研究的数据表明,这种差异仅能解释高血压患病率差异的一小部分。澳大利亚研究中较高的血压水平和较高的高血压患病率与澳大利亚45岁及以上男性和女性中脑血管疾病死亡率比美国高40%-55%(1968-1977年)的情况相符。1978年在澳大利亚,这种差异导致了超过4200例额外死亡(占年死亡率的4%),其中600例发生在65岁以下的男性和女性中。澳大利亚其他高血压疾病的死亡率也高于美国,这进一步支持了澳大利亚人群血压和高血压相关死亡率高于美国的观点。

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