Char D H, Ablin A, Beckstead J
Ann Ophthalmol. 1984 Sep;16(9):867-70, 872-3.
Four cases of different types of orbital, benign and malignant histiocytosis syndromes are presented to demonstrate the diagnostic presentation, medical evaluation, and therapy of these diseases with orbital involvement. Newer concepts have altered our understanding of the pathophysiology of histiocytic syndromes. An abnormality of Langerhans' cells and the T-cell suppressor population appears to be important in the development of histiocytosis. It is important for the ophthalmologist to be aware that histiocytic lesions of the orbit may be an indication of widespread and at times life-threatening disease.
本文介绍了4例不同类型的眼眶良性和恶性组织细胞增多症综合征，以展示这些累及眼眶疾病的诊断表现、医学评估及治疗。新的概念改变了我们对组织细胞增多症综合征病理生理学的理解。朗格汉斯细胞和T细胞抑制群体的异常似乎在组织细胞增多症的发展中起重要作用。眼科医生必须意识到，眼眶组织细胞病变可能预示着广泛且有时会危及生命的疾病。
