正常青春期男孩局部骨矿物质与总骨矿物质之间的关系。

Relationship between local and total bone mineral in normal pubertal boys.

作者信息

Krabbe S, Gotfredsen A, Christiansen C

出版信息

Eur J Pediatr. 1984 Dec;143(2):149-51. doi: 10.1007/BF00445805.

Abstract

The bone mineral content of the distal forearm (BMC) using single-photon absorptiometry and total body bone mineral (TBBM) using dual-photon absorptiometry were determined in 19 normal boys at different pubertal stages. A highly significant correlation between BMC and TBBM was seen (r = 0.78, P less than 0.001) with a standard error of estimate (SEE) of 13%. Subgroups of early and late pubertal stages did not show any significant differences in the regression lines indicating an identical relationship between BMC and TBBM at various stages of pubertal development although great changes in bone mineral content take place. Due to high accuracy and reproducibility of both methods, which are non-invasive and harmless, measurement of BMC is suitable to estimate changes in total mineral content of the body. This may be of importance in various diseases with disturbance in growth and bone metabolism.

摘要

采用单光子吸收法测定了19名处于不同青春期阶段的正常男孩的远端前臂骨矿物质含量（BMC），并采用双光子吸收法测定了全身骨矿物质（TBBM）。结果显示BMC与TBBM之间存在高度显著的相关性（r = 0.78，P < 0.001），估计标准误差（SEE）为13%。青春期早期和晚期亚组的回归线未显示出任何显著差异，这表明尽管骨矿物质含量发生了巨大变化，但在青春期发育的各个阶段，BMC与TBBM之间的关系是相同的。由于这两种方法具有高精度和可重复性，且无创无害，因此BMC的测量适合于估计身体总矿物质含量的变化。这在各种生长和骨代谢紊乱的疾病中可能具有重要意义。