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[慢性胰腺炎中胰管出血。4例报告及文献研究]

[Wirsung's duct hemorrhage in chronic pancreatitis. Report of 4 cases and study of the literature].

作者信息

Le Neel J C, Leborgne J, Heloury Y, Deret C, Lavignolle A, Malvy P

出版信息

J Chir (Paris). 1984 Nov;121(11):649-53.

PMID:6335510
Abstract

Hemorrhage from Wirsung's canal complicated chronic pancreatitis in 4 patients. Excision (2 cephalic and 1 corporeocaudal) in 3 cases provided successful results, the 4th patient dying from intraperitoneal rupture of the false cyst responsible for the hemorrhage, during recurrence of the latter after simple ligature. A literature review indicated pancreatic disease, mainly chronic, as the cause in 76.5% of the 64 cases documented. Diagnosis is difficult from clinical findings, and is dependent mainly on results of endoscopy and particularly retrograde catheterization of the papilla, while arteriography is essential for confirmation of the diagnosis and the site of the lesion, and for assisting choice of therapy. When a chronic pancreatitis exists, the only logical attitude is selective excision, mortality being minimal (5%). Embolization could be a valid method for ensuring hemostasis temporarily to allow delayed radical surgery.

摘要

4例患者因慢性胰腺炎并发胰管出血。3例患者接受了切除术(2例为胰头切除,1例为胰体尾切除),手术成功;第4例患者在单纯结扎术后出血复发时,因假性囊肿破裂致腹腔内出血死亡。文献回顾显示,在有记录的64例病例中,76.5%的病因是胰腺疾病,主要是慢性胰腺炎。临床检查难以确诊,主要依赖内镜检查结果,尤其是乳头逆行插管造影,而动脉造影对于确诊、确定病变部位及辅助治疗方案的选择至关重要。存在慢性胰腺炎时,唯一合理的治疗方法是选择性切除,死亡率极低(5%)。栓塞术可能是一种有效的临时止血方法,以便择期进行根治性手术。

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