Marchesoni C, De Marco P, Ronconi G F, Miottello P G
Pediatr Med Chir. 1983 Nov-Dec;5(6):571-3.
It is known that, particularly in Nordic States, many patients undergoing antiepileptic therapy with Phenobarbital and Phentoin present disorders of the phospho-calcium metabolism, both clinical and biochemical. For what concerns the mediterranean area, few are the papers written concerning this subject in these last years. In this paper we attempt to provide a "case study" contribution (100 cases) to enable us to study the above-mentioned alteration focusing on an area half way between Central and Southern Europe. The Authors discuss the possible mechanism implicated in this affection.
众所周知,尤其是在北欧国家,许多接受苯巴比妥和苯妥英抗癫痫治疗的患者出现了磷钙代谢紊乱,包括临床和生化方面的紊乱。在地中海地区,近年来关于这一主题的论文很少。在本文中,我们试图提供一份“案例研究”报告(100例),以便我们能够专注于中欧和南欧之间的一个地区来研究上述改变。作者们讨论了与此病症相关的可能机制。