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粒细胞-巨噬细胞(GM)集落形成的组织抑制剂

Tissue inhibitors of granulocyte-macrophage (GM) colony formation.

作者信息

Szmitkowski M, Prokopowicz J, Kondracka E

出版信息

Arch Immunol Ther Exp (Warsz). 1984;32(4):447-50.

PMID:6335960
Abstract

The effect of mice tissue homogenates on the inhibition of granulocyte-macrophage colony formation in vitro was studied. The potent inhibitory activity was displayed by homogenate from liver. The lowest values were found in the kidney and heart. An interrelationship between the rate of inhibition and protein concentration in the homogenates was noted. Biological role and the type of inhibitory activity are briefly discussed.

摘要

研究了小鼠组织匀浆对体外粒细胞-巨噬细胞集落形成的抑制作用。肝脏匀浆表现出强大的抑制活性。在肾脏和心脏中发现的值最低。注意到匀浆中抑制率与蛋白质浓度之间的相互关系。简要讨论了其生物学作用和抑制活性类型。

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