Tsung P K, Price J, Holly F J
Inflammation. 1983 Sep;7(3):257-67. doi: 10.1007/BF00917263.
Lysosomal enzyme activities in rabbit ocular tissues were examined at various times after the intravitreal injection of endotoxin. Lysosomal enzyme activities in the aqueous, vitreous, and pigment epithelium-choroid were elevated 3 h after injection. It is deduced from the fluorescein-labeled dextran and SDS-polyacrylamide gel electrophoresis analysis of the aqueous, vitreous, and pigment epithelium-choroid from endotoxin injected rabbits that the elevation of lysosomal enzyme activities are probably due to a breakdown in blood-ocular barriers.
在玻璃体内注射内毒素后的不同时间，检测了兔眼组织中的溶酶体酶活性。注射后3小时，房水、玻璃体和色素上皮-脉络膜中的溶酶体酶活性升高。通过对注射内毒素的兔的房水、玻璃体和色素上皮-脉络膜进行荧光素标记葡聚糖和SDS-聚丙烯酰胺凝胶电泳分析推断，溶酶体酶活性的升高可能是由于血眼屏障的破坏。
