Uehara T, Nishimura T, Hayashida K, Kozuka T
J Cardiogr. 1984 Dec;14(4):645-53.
For diagnosing myocardial infarction by myocardial scintigraphy using 201TlCl, the following two items were compared: 1) The diagnostic accuracy of visual evaluation of myocardial planar images versus that of single photon emission computed tomography (SPECT) images. 2) The diagnostic accuracy of qualitative and quantitative evaluations of SPECT images. The planar and SPECT methods were performed for 81 subjects consisting of 41 patients having myocardial infarction and 40 normal persons. Receiver operator characteristic (ROC) analysis, which is most objective in evaluation of visual diagnosis, was also used. To analyze quantitative diagnosis by ROC analysis, the normal range of circumferential profile analysis of myocardial short-axial tomography was determined by assessing five step divisions (less than 1 SD, 1-1.7 SD, 1.7-2.3 SD, 2.3-3 SD, and more than 3 SD) from 10 normal cases. Four physicians and three laboratory technicians familiar with myocardial images diagnosed the myocardial planar images and SPECT images individually. The results were analyzed and the ROC curves were constructed. The results indicated that image diagnosis by SPECT was superior to that by the visual planar method for all persons. The physicians who had more experience in diagnosing myocardial images made more accurate diagnosis. However, quantitative SPECT image diagnosis was superior to visual SPECT image diagnosis. Thus, with the input of data of the normal range of quantitative SPECT image diagnosis into the computer, the prospects of accurate computer assessments of myocardial infarctions were posed.(ABSTRACT TRUNCATED AT 250 WORDS)
对于使用氯化铊锝(201TlCl)进行心肌闪烁显像诊断心肌梗死,比较了以下两项:1)心肌平面图像视觉评估与单光子发射计算机断层扫描(SPECT)图像的诊断准确性。2)SPECT图像定性和定量评估的诊断准确性。对81名受试者进行了平面和SPECT检查,其中包括41名心肌梗死患者和40名正常人。还采用了评估视觉诊断时最客观的受试者工作特征(ROC)分析。为通过ROC分析进行定量诊断,通过评估10例正常病例的五个步骤划分(小于1个标准差、1 - 1.7个标准差、1.7 - 2.3个标准差、2.3 - 3个标准差和大于3个标准差)来确定心肌短轴断层扫描圆周轮廓分析的正常范围。四名熟悉心肌图像的医生和三名实验室技术人员分别对心肌平面图像和SPECT图像进行诊断。分析结果并构建ROC曲线。结果表明,对于所有人而言,SPECT图像诊断优于视觉平面法诊断。在诊断心肌图像方面经验更丰富的医生诊断更准确。然而,定量SPECT图像诊断优于视觉SPECT图像诊断。因此,将定量SPECT图像诊断的正常范围数据输入计算机,提出了准确计算机评估心肌梗死的前景。(摘要截短于250字)