Ryhänen R, Närhi M, Puhakainen E, Hänninen O, Kontturi-Närhi V
J Dent Res. 1983 Jan;62(1):20-3. doi: 10.1177/00220345830620010501.
Pseudocholinesterase (PCE) activity in oral fluid of 31 male and 24 female subjects was determined using butyrylthiocholine iodide as substrate. Males had approximately twice as much salivary PCE activity as did females [4.8 +/- 2.4 (S.D.) U/1 and 2.2 +/- 1.5 (S.D.) U/1, respectively]. The activity was not much affected by salivary flow rate, although in men it was a little higher in stimulated than in unstimulated saliva. Salivary PCE activity showed diurnal variation. Accordingly, activities were about three times greater at four a.m. than at four p.m. Parotid PCE activity correlated with that of whole saliva in both men and women. PCE activity in crevicular fluid (four subjects) was 120 +/- 48 (S.D.) U/1. An elevation of PCE activity in oral fluid was found after experimental induction of gingival inflammation. However, the mean PCE activity of patients with clinical gingivitis was not significantly higher than that of healthy subjects, although some exceptionally high values were found. Sonicated samples of plaque did not contain any PCE activity. No correlation existed between PCE activities in saliva and serum.
以碘化丁酰硫代胆碱为底物，测定了31名男性和24名女性受试者口腔液中的假胆碱酯酶（PCE）活性。男性唾液中PCE活性约为女性的两倍[分别为4.8±2.4（标准差）U/1和2.2±1.5（标准差）U/1]。尽管男性中刺激唾液中的PCE活性略高于非刺激唾液，但该活性受唾液流速的影响不大。唾液PCE活性呈现昼夜变化。因此，凌晨4点的活性约为下午4点的三倍。男性和女性腮腺PCE活性与全唾液的PCE活性均相关。龈沟液（4名受试者）中的PCE活性为120±48（标准差）U/1。实验性诱导牙龈炎症后，发现口腔液中PCE活性升高。然而，临床牙龈炎患者的平均PCE活性虽有一些异常高值，但与健康受试者相比无显著差异。超声处理后的菌斑样本不含任何PCE活性。唾液和血清中的PCE活性之间不存在相关性。
