Nghiem D D, Corry R J, Picon-Mendez G, Lee H M
Urology. 1983 Jan;21(1):49-52. doi: 10.1016/0090-4295(83)90122-x.
Sexual impotence has been reported sixfold after sequential renal transplantation. The effects of race, age, diabetes mellitus, hypertension, uremia, arteriosclerosis (by ABI = ankle BP/brachial BP), penile blood flow (by PBI = penile BP/brachial BP), length of dialysis and transplantation, and patency of hypogastric arteries (by angiogram and operative description) on impotence were examined in a retrospective study of 61 male transplant patients followed from six to 108 months and a prospective study of 15 patients evaluated before and after transplantation with a six-month follow-up. Age (greater than forty years) was the only factor deleterious to male potency (potent patients 40.1 +/- 10.40 years vs impotent patients 48.6 +/- 10.06 years significant at p less than 0.006). Impotence did not correlate with ABI and PBI. Interruption of both hypogastric arteries is not necessarily related to impotence. Vascular impotence is more uncommon in renal transplant recipients than we had anticipated. Post-transplantation male impotence is perhaps best treated by penile prosthesis insertion.
据报道,序贯肾移植后性功能障碍的发生率增加了六倍。在一项对61例男性移植患者进行6至108个月随访的回顾性研究以及一项对15例患者在移植前后进行评估并随访6个月的前瞻性研究中,研究了种族、年龄、糖尿病、高血压、尿毒症、动脉硬化(通过踝臂指数=踝部血压/肱动脉血压)、阴茎血流(通过阴茎肱动脉指数=阴茎血压/肱动脉血压)、透析和移植时间以及下腹动脉通畅情况(通过血管造影和手术描述)对性功能障碍的影响。年龄(大于40岁)是对男性性功能有害的唯一因素(有性功能患者40.1±10.40岁,性功能障碍患者48.6±10.06岁,p<0.006时有显著差异)。性功能障碍与踝臂指数和阴茎肱动脉指数无关。双侧下腹动脉中断不一定与性功能障碍有关。肾移植受者中血管性性功能障碍比我们预期的更少见。移植后男性性功能障碍或许最好通过植入阴茎假体来治疗。